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Centella Asiatica Extract
→ Enhances collagen synthesis by +44 % (in-vitro).
→ Provides +72 % comfort improvement and -45 % redness reduction after 14 days (in-vivo).
DNA (Marine DNA Complex)
→ Promotes +38 % cell regeneration rate and improved dermal density.
→ Demonstrated antioxidant capacity and tissue-repair properties.
Vitamin E
→ Reduces oxidative stress markers by up to –58 % in 4 weeks.
→ Increases skin smoothness and elasticity, supporting barrier resilience.

Ameyezing™ – Sederma, France
→ Targets vascular and pigmented dark circles through melanin regulation and microcirculation improvement.
→ −28.6% melanin; −40% eye-bag volume after 2 months.
→ −55% oxidative stress; reinforces capillary walls and collagen.
Leontopod Stems GX™ – IRB/Sederma, Italy
→ Edelweiss stem cells rich in Leontopodic Acids A & B (3× stronger antioxidant than Vitamin C).
→ Protects collagen and hyaluronic acid.
→ −18% wrinkle depth; +95% elasticity in 40 days.
Sens’Hyal™ – Givaudan, France
→ Multi-molecular hyaluronic acid system for long-term hydration.
→ +58% hydration (1h), +23% elasticity (1w), −19% TEWL (4w).
→ Reinforces barrier and smooths fine lines.
Is this therapy tested on animals?
No. CALINACHI products are cruelty-free and not tested on animals. All products comply with EU cosmetic safety regulations and are dermatologically tested.
What is the value of purchasing this as a complete therapy set?
The complete set ensures all 3 products work synergistically — each step prepares the skin for maximum absorption and efficacy of the next product. The set offers a saving of approximately 15% compared to purchasing the individual products separately, while providing a complete professional-grade overnight skincare ritual.
What age group is this therapy recommended for?
The Regenerating Night Therapy is recommended for adults aged 30 and above, when the skin's natural cell renewal rate slows significantly and overnight repair becomes increasingly important. It is rated 4.79 out of 5.0 by over 450 verified customers.
Can I use this therapy on my neck and décolleté?
Yes. All products in the Regenerating Night Therapy are formulated for the face, neck, and décolleté. Apply the Night Cream generously to all three areas every evening for comprehensive overnight regeneration and anti-aging benefits.
How does this therapy differ from the Hydrating Day Therapy?
The Regenerating Night Therapy is a complete overnight repair system focused on cellular regeneration, collagen stimulation, and deep restoration — working with the skin's natural sleep cycle. The Hydrating Day Therapy is a daytime system focused on SPF30 protection, hydration, radiance, and eye contour care. Together, they form a complete 24-hour skincare ritual for the face, neck, and décolleté.
Is this therapy suitable for sensitive and mature skin?
Yes. The Regenerating Night Therapy is dermatologically tested and suitable for all skin types including sensitive and mature skin. The allergen-reduced fragrance and gentle formulation make it safe for reactive skin, while the advanced actives deliver meaningful anti-aging benefits for mature skin.
How does this therapy reduce redness and uneven skin tone?
Centella Asiatica reduces skin inflammation and redness through its triterpenoid compounds (Asiaticoside, Madecassoside). Zerumbone provides additional anti-inflammatory benefits. Together, they calm reactive skin, even out skin tone, and promote a clearer, more radiant complexion with consistent overnight use.
What is Edelweiss and why is it included?
Edelweiss (Leontopodium Alpinum) is an alpine plant with exceptional antioxidant properties — it contains Leontopodic Acid, one of the most powerful natural antioxidants known. It protects skin cells from UV-induced and environmental oxidative damage, supports collagen rejuvenation, and helps maintain skin firmness and elasticity over time.
Why is nighttime the best time for skin regeneration?
During sleep, the skin's natural repair and regeneration cycle is at its most active — cell turnover accelerates, collagen production increases, and the skin's barrier function is restored. The Regenerating Night Therapy is specifically formulated to work in synergy with this natural cycle, delivering actives that support cellular repair, collagen synthesis, and deep hydration when the skin can absorb and utilize them most effectively.
What are the key active ingredients across this therapy?
Marine DNA for cellular repair and overnight skin regeneration. Edelweiss for powerful antioxidant protection and collagen rejuvenation. Centella Asiatica for collagen synthesis, redness reduction, and skin healing. Hyaluronic Acid for deep hydration and fine line plumping. Zerumbone for anti-inflammatory and anti-aging benefits. Ameyezing™ complex for eye contour revitalization, puffiness reduction, and dark circle brightening.
What are the 3 steps of this therapy?
Step 1 — Cleanse: The Micellar Myst gently removes makeup, impurities, and daily buildup while toning and hydrating the skin. Step 2 — Treat: The Eye Contour Cream with Ameyezing™ targets puffiness, dark circles, and fine lines around the delicate eye area. Step 3 — Regenerate: The Regenerating Night Cream with Marine DNA, Centella Asiatica, and Hyaluronic Acid delivers intensive overnight repair, collagen stimulation, and deep hydration to the face, neck, and décolleté.
What is included in the Regenerating Night Therapy set?
The Regenerating Night Therapy is a complete 3-step overnight skincare system for the face, neck, décolleté, and eye contour — combining the Regenerating Night Cream, Eye Contour Cream, and Micellar Myst. It is formulated to work during the skin's natural sleep cycle to repair, regenerate, and restore a smooth, youthful complexion.